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EMIS 2017 Journal Articles 2017

Influence of Internalised Homonegativity on sexual risk behaviour of men who have sex with men in Spain

Sexuality & Culture, published online first 27 November 2021 (doi: 10.1007/s12119-021-09925-7).

Authors: İbrahim Sönmez, Cinta Folch, Nicolas Lorente, Rigmor C. Berg, Natalie Thurlby & Axel J. Schmidt

Abstract

In a sample of men who have sex with men (MSM) (N = 3436) in Spain who bear intrinsic HIV risk, we investigated how internalised homonegativity (IH) is associated with the number of non-steady male partners with condomless intercourse (as a proxy of sexual risk behaviour). Using structural equation modelling (SEM), we examined the relationship between IH and sexual risk behaviour, and mediating effects of HIV/PrEP knowledge and substance use during sex on this relationship. We found no direct association between IH and sexual risk behaviour, nor did IH influence substance use during sex. In line with our hypothesis, association between IH and sexual risk behaviour was significant when mediated by HIV/PrEP knowledge. We found that as IH increased, sexual risk behaviour decreased, because higher IH was associated with lower HIV/PrEP knowledge while higher HIV/PrEP knowledge was associated with increased non-condom use with non-steady partners. Substance use during sex was significantly associated with sexual risk behaviour. Our results emphasize the continuing importance of prevention strategies focused on behavioural changes and community level interventions, especially targeting substance use.

© 2021 Springer Nature Switzerland AG

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EMIS 2017 Journal Articles 2017

Awareness of, willingness to take PrEP and its actual use among Belgian MSM at high risk of HIV infection: secondary analysis of the Belgian European MSM internet survey

AIDS and Behavior, published online first 24 November 2021 (doi: 10.1007/s10461-021-03526-z).

Authors: Veerle Buffel, Thijs Reyniers, Caroline Masquillier, Estrelle Thunissen, Christiana Nöstlinger, Marie Laga, Edwin Wouters, Wim Vanden Berghe, Jessika Deblonde, Bea Vuylsteke

Abstract

We examined PrEP awareness, willingness to take it and early PrEP use among men who have sex with men (MSM) at increased risk of HIV acquisition in Belgium. This analysis of the Belgian EMIS online data of 2017–2018 adopts a cascade approach, with the following steps quantified as conditional probabilities: being eligible for, aware of, willing to take PrEP, and PrEP use. One out of three MSM was eligible to use PrEP according to the operationalized Belgian reimbursement criteria. PrEP awareness was lower among socioeconomically vulnerable MSM, MSM living outside large cities, MSM who were less open about their sexuality and those who did not identify as gay or homosexual. A lack of PrEP knowledge, a higher self-efficacy regarding safe sex, having a steady partner and reporting more symptoms of depression were related to unwillingness to use PrEP. Among those willing to take PrEP, less than one third were actually using PrEP. Not using PrEP was associated with living in small cities and experiencing financial problems.

Keywords: Awareness of and willingness to use PrEP; Cascade approach; Eligibility criteria; Men who have sex with men (MSM); Pre-exposure prophylaxis (PrEP) use.

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EMIS 2017 Journal Articles 2017

Changes in the prevalence of self-reported sexually transmitted bacterial infections from 2010 and 2017 in two large European samples of men having sex with men – is it time to re-evaluate STI-screening as a control strategy?

PLoS ONE, 2021; 16(3): e0248582 (doi: 10.1371/journal.pone.0248582).

Authors: Ulrich Marcus, Massimo Mirandola, Susanne B Schink, Lorenzo Gios, Axel J Schmidt

Abstract

Background/Objectives: Many European countries reported increased numbers of syphilis, gonorrhoea and chlamydia diagnoses among men who have sex with men (MSM) in recent years. Behaviour changes and increased testing are thought to drive these increases.

Methods: In 2010 and 2017, two large online surveys for MSM in Europe (EMIS-2010, EMIS-2017) collected self-reported data on STI diagnoses in the previous 12 months, diagnostic procedures, STI symptoms when testing, number of sexual partners, and sexual behaviours such as condom use during the last intercourse with a non-steady partner in 46 European countries. Multivariate regression models were used to analyse factors associated with diagnoses of syphilis, gonorrhoea/chlamydia, and respective diagnoses classified as symptomatic and asymptomatic. If applicable, they included country-level screening rates.

Results: Questions on STI diagnoses and sexual behaviours were answered by 156,018 (2010) and 125,837 (2017) participants. Between 2010 and 2017, overall diagnoses with gonorrhoea/chlamydia and syphilis increased by 76% and 83% across countries. Increases were more pronounced for asymptomatic compared to symptomatic infections. The proportion of respondents screened and the frequency of screening grew considerably. Condomless anal intercourse with the last non-steady partner rose by 62%; self-reported partner numbers grew. Increased syphilis diagnoses were largely explained by behavioural changes (including more frequent screening). Gonorrhoea/chlamydia increases were mainly explained by more screening and a change in testing performance. A country variable representing the proportion of men screened for asymptomatic infection was positively associated with reporting symptomatic gonorrhoea/chlamydia, but not syphilis.

Discussion/Conclusion: The positive association of country-level screening rates with the proportion of symptomatic infections with gonorrhoea/chlamydia may indicate a paradoxical effect of screening on incidence of symptomatic infections. Treatment of asymptomatic men might render them more susceptible to new infections, while spontaneous clearance may result in reduced susceptibility. Before expanding screening programmes, evidence of the effects of screening and treatment is warranted.

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EMIS 2017 Journal Articles 2017

Chemsex and diagnoses of syphilis, gonorrhoea and chlamydia among men who have sex with men in the UK: a multivariable prediction model using causal inference methodology

Sexually Transmitted Infections, 2021; 97:282-289. (doi: 10.1136/sextrans-2020-054629).

Authors: Louis MacGregor, Manik Kohli, Katharine J Looker, Ford Hickson, Peter Weatherburn, Axel J Schmidt, Katy M Turner

Abstract

Introduction: In the last decade diagnoses of most STIs have risen among men who have sex with men (MSM). Although a significant proportion of this is likely due to increased STI screening, understanding the role of behavioural drivers remains critical. We measure the associations between stimulant use to enhance and prolong sexual experiences (chemsex) and bacterial STI diagnoses in UK MSM, individually considering HIV-diagnosed MSM, pre-exposure prophylaxis (PrEP) users and other MSM.

Methods: We used the UK 2017-2018 European MSM Internet Survey data (n=9375). We constructed causal inference models using multivariable logistic regression, calculating adjusted OR (aOR) and 95% CI of the associations between participation in recent (≤12 months) exclusively dyadic or multipartner chemsex versus no chemsex and recent self-reported diagnoses of syphilis, gonorrhoea and chlamydia.

Results: Among MSM with an HIV diagnosis, 25% of users indicated recent multipartner chemsex, vs 28% of PrEP users and 5% of other MSM. Adjusting for age, ethnicity, UK birth, cis-trans status, sexual identity, education, settlement size and relationship status, participation in recent multipartner chemsex versus no chemsex was associated with greater odds of recent syphilis, gonorrhoea and chlamydia diagnosis. aORs for recent syphilis, gonorrhoea and chlamydia diagnoses were 2.6 (95% CI 1.7 to 4.1), 3.9 (95% CI 2.6 to 5.8) and 2.9 (95% CI 1.9 to 4.3), respectively, in HIV-diagnosed MSM; 1.9 (95% CI 1.1 to 3.3), 2.9 (95% CI 2.0 to 4.2) and 1.9 (95% CI 1.3 to 2.8), respectively, in PrEP users; and 4.0 (95% CI 2.3 to 6.9), 2.7 (95% CI 1.9 to 3.8) and 2.3 (95% CI 1.6 to 3.4), respectively, in other MSM. Conversely, exclusively dyadic chemsex had no significant associations with bacterial STI diagnoses among HIV-diagnosed MSM, only gonorrhoea (aOR 2.4, 95% CI 1.2 to 4.7) among PrEP users and syphilis (aOR 2.8, 95% CI 1.4 to 5.6) among other MSM.

Discussion: Multipartner chemsex may drive the association between chemsex and bacterial STI diagnoses and thus should be the focus of future tailored chemsex interventions. Additionally, PrEP acceptability among MSM and particularly chemsex participants has generated an emergent group suitable for such interventions.

Keywords: Chlamydia trachomatis; gay men; gonorrhoea; sexual behaviour; syphilis.

© Author(s) (or their employer(s)) 2021. No commercial re-use. Published by BMJ.

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EMIS 2010 Journal Articles 2010

Changes in the prevalence of self-reported sexually transmitted bacterial infections from 2010 and 2017 in two large European samples of men having sex with men – is it time to re-evaluate STI-screening as a control strategy?

PLoS ONE, 2021; 16(3): e0248582 (doi: 10.1371/journal.pone.0248582).

Authors: Ulrich Marcus, Massimo Mirandola, Susanne B Schink, Lorenzo Gios, Axel J Schmidt

Abstract

Background/Objectives: Many European countries reported increased numbers of syphilis, gonorrhoea and chlamydia diagnoses among men who have sex with men (MSM) in recent years. Behaviour changes and increased testing are thought to drive these increases.

Methods: In 2010 and 2017, two large online surveys for MSM in Europe (EMIS-2010, EMIS-2017) collected self-reported data on STI diagnoses in the previous 12 months, diagnostic procedures, STI symptoms when testing, number of sexual partners, and sexual behaviours such as condom use during the last intercourse with a non-steady partner in 46 European countries. Multivariate regression models were used to analyse factors associated with diagnoses of syphilis, gonorrhoea/chlamydia, and respective diagnoses classified as symptomatic and asymptomatic. If applicable, they included country-level screening rates.

Results: Questions on STI diagnoses and sexual behaviours were answered by 156,018 (2010) and 125,837 (2017) participants. Between 2010 and 2017, overall diagnoses with gonorrhoea/chlamydia and syphilis increased by 76% and 83% across countries. Increases were more pronounced for asymptomatic compared to symptomatic infections. The proportion of respondents screened and the frequency of screening grew considerably. Condomless anal intercourse with the last non-steady partner rose by 62%; self-reported partner numbers grew. Increased syphilis diagnoses were largely explained by behavioural changes (including more frequent screening). Gonorrhoea/chlamydia increases were mainly explained by more screening and a change in testing performance. A country variable representing the proportion of men screened for asymptomatic infection was positively associated with reporting symptomatic gonorrhoea/chlamydia, but not syphilis.

Discussion/Conclusion: The positive association of country-level screening rates with the proportion of symptomatic infections with gonorrhoea/chlamydia may indicate a paradoxical effect of screening on incidence of symptomatic infections. Treatment of asymptomatic men might render them more susceptible to new infections, while spontaneous clearance may result in reduced susceptibility. Before expanding screening programmes, evidence of the effects of screening and treatment is warranted.

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EMIS 2017 Journal Articles 2017

Potential alcohol use disorder among MSM in Ireland – Findings from the European MSM internet survey (EMIS 2017)

Drug and Alcohol Dependence, 2021; 223: 108698 (doi: 10.1016/j.drugalcdep.2021.108698).

Authors: Fionn P. Daly, Kate O’Donnell, Martin P. Davoren, Chris Noone, Peter Weatherburn, Mick Quinlan, Bill Foley, Derval Igoe, Peter M. Barrett

Abstract

Background: Alcohol consumption is a major public health concern in Ireland. Alcohol use disorder (AUD) disproportionately affects men who have sex with men (MSM). However, little is known about the prevalence of AUD in this group in Ireland specifically, and the characteristics of MSM who may struggle with this.

Methods: The European MSM Internet Survey 2017 was an online, self-completed, anonymous questionnaire among MSM in Ireland. Standardised questions were used to explore a variety of topics. The validated CAGE-4 questionnaire was used to screen for potential AUD, defined as a CAGE-4 score of ≥2 out of 4. Multivariable-adjusted logistic regression analysis was used to identify factors associated with potential AUD.

Results: In total, 1793 MSM met inclusion criteria. 31 % screened positive for AUD. We observed higher odds of possible AUD among MSM who were bisexual (vs. gay/homosexual) (aOR 1.48 95 %CI 1.01–2.18), native to Ireland (vs. non-native) (aOR 1.49 95 %CI 1.12–1.96), unemployed (vs. employed) (aOR 1.80 95 %CI 1.02–3.16), had used illicit drugs in the previous year (vs. none) (cannabis only, aOR 1.74 95 %CI 1.14–2.63) (other illicit drugs, aOR 2.28 95 %CI 1.67–3.09), reported anxiety/depression (vs. none) (aOR 1.73 95 %CI 1.12–2.66), and MSM who experienced homophobic abuse (vs. never) (aOR 1.55 95 %CI 1.09–2.22). Student MSM were less likely to screen positive for AUD (vs. employed) (aOR 0.65 95 %CI 0.46−0.93).

Conclusions: The prevalence of AUD appears to be higher in the MSM population compared to the general male population in Ireland. Targeted interventions may be warranted to reduce the burden of AUD among MSM.

Keywords: Men who have sex with men (MSM); Alcohol use disorder (AUD); Drug use; Depression/Anxiety; Homophobia; HIV / AIDS

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EMIS 2017 Journal Articles 2017

Structural stigma and sexual minority men’s depression and suicidality: A multilevel examination of mechanisms and mobility across 48 countries

Journal of Abnormal Psychology, 2021; 130(7):713-726 (doi: 10.1037/abn0000693)

Authors: John E Pachankis, Mark L Hatzenbuehler, Richard Bränström, Axel J Schmidt, Rigmor C Berg, Kai Jonas, Michal Pitoňák, Sladjana Baros, Peter Weatherburn

Abstract

Sexual minority men are at greater risk of depression and suicidality than heterosexuals. Stigma, the most frequently hypothesized risk factor for this disparity, operates across socioecological levels-structural (eg. laws), interpersonal (eg. discrimination), and individual (eg. self-stigma). Although the literature on stigma and mental health has focused on interpersonal and individual forms of stigma, emerging research has shown that structural stigma is also associated with adverse mental health outcomes. However, there is limited data on whether changes in structural stigma, such as when a stigmatized person moves to a lower stigma context, affect mental health, and on the mechanisms underlying this association. To address these questions, we use data from the 2017/18 European Men-who-have-sex-with-men Internet Survey (n = 123,428), which assessed mental health (ie. Patient Health Questionnaire) and psychosocial mediators (ie. sexual orientation concealment, internalized homonegativity, and social isolation). We linked these data to an objective indicator of structural stigma related to sexual orientation-including 15 laws and policies as well as aggregated social attitudes-in respondents’ countries of origin (N = 178) and receiving countries (N = 48). Among respondents who still live in their country of birth (N = 106,883), structural stigma was related to depression and suicidality via internalized homonegativity and social isolation. Among respondents who moved from higher-to-lower structural stigma countries (n = 11,831), longer exposure to the lower structural stigma environments of their receiving countries was associated with a significantly: 1) lower risk of depression and suicidality; 2) lower odds of concealment, internalized homonegativity, and social isolation; and 3) smaller indirect effect of structural stigma on mental health through these mediators. This study provides additional evidence that stigma is a sociocultural determinant of mental health.

© 2021 American Psychological Association 2021, ISSN: 0021-843X

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EMIS 2017 International reports 2017

EMIS-2017: Community Reports Europe

We thank our network partners for their translations of the following Community Reports.

The 3rd EMIS-2017 Community Report, published 14 August 2021, covers the stress factors affecting mental and sexual health and well-being and was coordinated by Mick Quinlan (Gay Health Network, Dublin, Ireland). It has been translated into the six most commonly spoken (apart from English) languages in Europe: German, Russian, French, Turkish, Italian, and Spanish, as well as into Arabic, Czech, and Portuguese. The 3rd community report was funded by Ireland’s Health Services (HSE)

The 2nd EMIS-2017 Community Report, published 27 November 2020, focuses on gay men living with HIV in Europe and was coordinated by Mick Quinlan (Gay Health Network, Dublin, Ireland). It has been translated into the seven most commonly spoken (apart from English) languages in Europe: German, Russian, French, Turkish, Italian, Polish, and Spanish, as well as into Arabic, Czech, and Portuguese. The 2nd community report was funded by Ireland’s Health Services (HSE)

The 1st EMIS-2017 Community Report targeted at EMIS respondents and MSM in general was published in 31 languages by the end of 2018. We thank our network partners for their contributions and translations, and particularly the German NGO Deutsche AIDS-Hilfe for leading the process, and the Swiss AIDS Federation for financial support.

The first Community Report describes safer sex knowledge (including knowledge on Pre-Exposure Prophylaxis (PrEP) and Undetectable=Untransmittable (U=U). The English version was first presented at AIDS2018 in Amsterdam. The Philippines opted out from the 1st Community Report, so it covers 49, not 50, countries.

3rd EMIS-2017 Community Report

3rd EMIS-2017 Community Report (Arabic)

3rd EMIS-2017 Community Report (Czech)

3rd EMIS-2017 Community Report (English)

3rd EMIS-2017 Community Report (French)

3rd EMIS-2017 Community Report (German)

3rd EMIS-2017 Community Report (Italian)

3rd EMIS-2017 Community Report (Portuguese)

3rd EMIS-2017 Community Report (Russian)

3rd EMIS-2017 Community Report (Spanish)

3rd EMIS-2017 Community Report (Turkish)

2nd EMIS-2017 Community Report

2nd EMIS-2017 Community Report (Arabic)

2nd EMIS-2017 Community Report (Czech)

2nd EMIS-2017 Community Report (English)

2nd EMIS-2017 Community Report (French)

2nd EMIS-2017 Community Report (German)

2nd EMIS-2017 Community Report (Italian)

2nd EMIS-2017 Community Report (Polish)

2nd EMIS-2017 Community Report (Portuguese)

2nd EMIS-2017 Community Report (Russian)

2nd EMIS-2017 Community Report (Spanish)

2nd EMIS-2017 Community Report (Turkish)

1st EMIS-2017 Community Report

1st EMIS-2017 Community Report (Arabic)

1st EMIS-2017 Community Report (Bulgarian)

1st EMIS-2017 Community Report (Croatian)

1st EMIS-2017 Community Report (Czech)

1st EMIS-2017 Community Report (Danish)

1st EMIS-2017 Community Report (Dutch)

1st EMIS-2017 Community Report (English)

1st EMIS-2017 Community Report (Estonian)

1st EMIS-2017 Community Report (Finnish)

1st EMIS-2017 Community Report (French)

1st EMIS-2017 Community Report (Switzerland-French)

1st EMIS-2017 Community Report (German)

1st EMIS-2017 Community Report (Switzerland-German)

1st EMIS-2017 Community Report (Greek)

1st EMIS-2017 Community Report (Hebrew)

1st EMIS-2017 Community Report (Hungarian)

1st EMIS-2017 Community Report (Icelandic)

1st EMIS-2017 Community Report (Italian)

1st EMIS-2017 Community Report (Switzerland-Italian)

1st EMIS-2017 Community Report (Latvian)

1st EMIS-2017 Community Report (Lithuanian)

1st EMIS-2017 Community Report (Macedonian)

1st EMIS-2017 Community Report (Norwegian)

1st EMIS-2017 Community Report (Polish)

1st EMIS-2017 Community Report (Portuguese)

1st EMIS-2017 Community Report (Romanian)

1st EMIS-2017 Community Report (Russian)

1st EMIS-2017 Community Report (Serbian)

1st EMIS-2017 Community Report (Slovak)

1st EMIS-2017 Community Report (Slovenian)

1st EMIS-2017 Community Report (Spanish)

1st EMIS-2017 Community Report (Swedish)

1st EMIS-2017 Community Report (Turkish)

1st EMIS-2017 Community Report (Ukrainian)

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EMIS 2017 Journal Articles 2017

Measures of HIV pre‐exposure prophylaxis uptake among gay, bisexual, and other men who have sex with men in Canada and demographic disparities among those at elevated likelihood for HIV acquisition

AIDS and Behavior, 2021; 25:3638–3650 (doi: 10.1007/s10461-021-03336-3).

Authors: Sean Colyer, Nathan J Lachowsky, Axel J Schmidt, Barry D Adam, Dana Paquette, Trevor A Hart, David J Brennan, Martin Blais, Abigail E Kroch

Abstract

HIV pre-exposure prophylaxis (PrEP) is an effective prevention tool being scaled up in Canada. We describe PrEP uptake and identify demographic correlates of uptake among gay, bisexual, and other men who have sex with men (gbMSM) at elevated HIV risk using data from an online survey of gbMSM residing in Canada between Oct 2017 and Jan 2018. Among the 969 participants at elevated HIV risk who had recently tested for HIV, 96.0%, 83.3%, 72.6%, and 39.7% reported awareness, knowledge, acceptability, and pursuit of PrEP, respectively; 27.1% had ever and 24.6% were currently taking PrEP. The strongest correlate of PrEP uptake was living in a city of ≥ 500,000 inhabitants; others included being out to all or almost all family, friends, and colleagues regarding sexual attraction to men, greater financial coping, and being 30–49 years of age. Improved upscaling of PrEP in Canada may be accomplished through consideration of these disparities.

Keywords: MSM; pre-exposure prophylaxis (PrEP); PrEP eligibility; PrEP access; PrEP delivery

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EMIS 2017 Journal Articles 2017

Der Europäische MSM Internet Survey als Grundlage für die Präventionsarbeit in Deutschland für Männer, die Sex mit Männern haben

Bundesgesundheitsblatt – Gesundheitsforschung – Gesundheitsschutz (doi: 10.1007/s00103-021-03429-3)

Authors: Ulrich Marcus & Susanne B. Schink

Abstract

Background: Sexual minorities are highly vulnerable to sexually transmitted infections (STIs), mental health problems such as depression and suicidality, and substance use- associated health and social problems. 

Research question: We describe selected findings from the European MSM Internet Survey (EMIS) 2017, one of the largest online surveys of men who have sex with men, and discuss their implications for prevention in MSM in Germany.

Materials and methods: The overall aim of EMIS-2017 was to collect data for planning HIV and STI prevention and treatment programs. The target population were men living in Europe who have sex with men and/or are attracted to men. The questionnaire contained questions on demography, morbidities, beha- viour, needs and interventions. Participants were recruited mainly via two popular online dating platforms from 10/2017 to 01/2018.

Results and discussion: EMIS-2017 shows that MSM are severely affected by psychological stress and STIs. In terms of psychological stress, younger MSM suffer in particular from depressive disorders and suicidality, while the use of alcohol and other psychoactive substances is of concern among older MSM. MSM are more often affected by STIs than the heterosexual majority population. Many STIs are a- or pauci-symptomatic; thus, screening based on risk-assessment is favoured to detect infections. However, for the time being, for some STIs there is no medical and/or public health evidence to support treatment of asymptomatic infections. EMIS-2017 identified needs by subgroups as far as knowledge gaps on PEP (HIV post-exposure prophylaxis) and PrEP (HIV pre-exposure prophylaxis), being reached by information and prevention offers as well as insufficient uptake of such offers.

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